INGREDIET HERBS

gm

1> Gymnema sylvestre

1.19

2> Syzygium cumini

0.38

3> Tiniospora cordifolia

0.475

4> Curcuma Longa

0.24

5> Ficus Racemosa

0.19

6> Momordica Charantia

0.24

7> Acacia catechu

0.12

8> Emblica officinalis

0.24

9> Pterocarpus marsupium

0.355

10> Cinnamomum tamala

0.24

11> Cyperus rotundus

0.19

12> Azadirachta indica

0.38

13> Purified asphaltum

0.24

14> Trigonella foenum – graecum

0.14

15> Bhang bhasm

0.03

16> Yasad bhasam

0.03

17> Guar gum

0.14

18> Gum acacia

0.14

19> Sodium benzoate

0.015

Gymnema Sylvestre

Other Names:

Gemnema Melicida, Gimnema, Gur-Mar, Gurmar, Gurmarbooti, Gymnema montanum, Gymnema sylvestre, Gymnéma, Gymnéma Sylvestre, Madhunashini, Merasingi, Meshashringi, Miracle Plant, Periploca sylvestris, Shardunika, Vishani.

Gymnema is a woody climbing shrub native to India and Africa. The leaves are used to make medicine. Gymnema has a long history of use in India’s Ayurvedic medicine. The Hindi name, gurmar, means "destroyer of sugar."

How does it work?

Gymnema contains substances that decrease the absorption of sugar from the intestine. Gymnema may also increase the amount of insulin in the body and increase the growth of cells in the pancreas, which is the place in the body where insulin is made.

Read more click - Gymnema sylvestre: A Memoir

Syzygium Cumini

Syzygium cumini (S. cumini) (L.) Skeels (jambolan) is one of the widely used medicinal plants in the treatment of various diseases in particular diabetes. The present review has been primed to describe the existing data on the information on botany, phytochemical constituents, traditional uses and pharmacological actions of S. cumini (L.) Skeels (jambolan). Electronic database search was conducted with the search terms of Eugenia jambolana, S. cumini, jambolan, common plum and java plum. The plant has been viewed as an antidiabetic plant since it became commercially available several decades ago. During last four decades, numerous folk medicine and scientific reports on the antidiabetic effects of this plant have been cited in the literature. The plant is rich in compounds containing anthocyanins, glucoside, ellagic acid, isoquercetin, kaemferol and myrecetin. The seeds are claimed to contain alkaloid, jambosine, and glycoside jambolin or antimellin, which halts the diastatic conversion of starch into sugar. The vast number of literatures found in the database revealed that the extracts of different parts of jambolan showed significant pharmacological actions. We suggest that there is a need for further investigation to isolate active principles which confer the pharmacological action. Hence identification of such active compounds is useful for producing safer drugs in the treatment of various ailments including diabetes.

Read more click - Syzygium cumini (L.) Skeels: A review of its phytochemical constituents and traditional uses

Tinospora Cordifolia

(Wikipedia) Tinospora cordifolia, which is known by the common names Guduchi and Giloy, is an herbaceous vine of the family Menispermaceae indigenous to the tropical areas of India, Myanmar and Sri Lanka.

(Webmd) Tinospora cordifolia is a shrub that is native to India. Its root, stems, and leaves are used in Ayurvedic medicine.

Tinospora cordifolia is used for diabetes, high cholesterol, allergic rhinitis (hay fever), upset stomach, gout, lymphoma and other cancers, rheumatoid arthritis (RA), hepatitis, peptic ulcer disease (PUD), fever, gonorrhea, syphilis, and to boost the immune system.

How does it work?

Tinospora cordifolia contains many different chemicals that might affect the body. Some of these chemicals have antioxidant effects. Others might increase the activity of the body's immune system. Some chemicals might have activity against cancer cells in test animals. Most research has been done in test tubes or in animals. There isn’t enough information to know the effects of Tinospora cordifolia in the human body.

Natural products with medicinal value are gradually gaining importance in clinical research due to their well-known property of no side effects as compared to drugs. Tinospora cordifolia commonly named as “Guduchi” is known for its immense application in the treatment of various diseases in the traditional ayurvedic literature. Recently the discovery of active components from the plant and their biological function in disease control has led to active interest in the plant across the globe. Our present study in this review encompasses (i) the genetic diversity of the plant and (ii) active components isolated from the plant and their biological role in disease targeting. The future scope of the review remains in exploiting the biochemical and signaling pathways affected by the compounds isolated from Tinospora so as to enable new and effective formulation in disease eradication.

Read more click - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644751/

Curcuma Longa

The turmeric (Curcuma longa L. rhizomes) EtOH extract significantly suppressed an increase in blood glucose level in type 2 diabetic KK-A(y) mice. In an in vitro evaluation, the extract stimulated human adipocyte differentiation in a dose-dependent manner and showed human peroxisome proliferator-activated receptor (PPAR)-gamma ligand-binding activity in a GAL4-PPAR-gamma chimera assay. The main constituents of the extract were identified as curcumin, demethoxycurcumin, bisdemethoxycurcumin, and ar-turmerone, which had also PPAR-gamma ligand-binding activity. These results indicate that turmeric is a promising ingredient of functional food for the prevention and/or amelioration of type 2 diabetes and that curcumin, demethoxycurcumin, bisdemethoxycurcumin, and ar-turmerone mainly contribute to the effects via PPAR-gamma activation.

Click to read more -

1. Hypoglycemic effects of turmeric (Curcuma longa L. rhizomes) on genetically diabetic KK-Ay mice.

2. EFFECT OF CURCUMA LONGA FREEZE DRIED RHIZOME POWDER WITH MILK IN STZ INDUCED DIABETIC RATS

3. HYPOGLYCEMIC, HYPOLIPIDEMIC AND ANTIOXIDANT PROPERTIES OF COMBINATION OF CURCUMIN FROM CURCUMA LONGA, Linn, AND PARTIALLY PURIFIED PRODUCT FROM ABROMA AUGUSTA, Linn. IN STREPTOZOTOCIN INDUCED DIABETES .

Ficus Racemosa

Ficus racemosa Linn. (Moraceae) is a popular medicinal plant in India, which has long been used in Ayurveda, the ancient system of Indian medicine, for various diseases/disorders including diabetes, liver disorders, diarrhea, inflammatory conditions, hemorrhoids, respiratory, and urinary diseases. F. racemosa is pharmacologically studied for various activities including antidiabetic, antipyretic, anti-inflammatory, antitussive, hepatoprotective, and antimicrobial activities. A wide range of phytochemical constituents have been identified and isolated from various parts of F. racemosa. In this review, a comprehensive account of its traditional uses, phytochemical constituents, and pharmacological effects is presented in view of the many recent findings of importance on this plant.

Read more click - http://www.ncbi.nlm.nih.gov/pubmed/20645741

Momordica Charantia

It has been estimated that up to one-third of patients with diabetes mellitus use some form of complementary and alternative medicine. Momordica charantia (bitter melon) is a popular fruit used for the treatment of diabetes and related conditions amongst the indigenous populations of Asia, South America, India and East Africa. Abundant pre-clinical studies have documented the anti-diabetic and hypoglycaemic effects of M. charantia through various postulated mechanisms. However, clinical trial data with human subjects are limited and flawed by poor study design and low statistical power. The present article reviews the clinical data regarding the anti-diabetic potentials of M. charantia and calls for better-designed clinical trials to further elucidate its possible therapeutic effects.

Read more - http://www.ncbi.nlm.nih.gov/pubmed/19825210

Acacia Catechu

Catechu is an herb. The leaves, shoots, and wood are used to make medicine. The two types of catechu, black catechu and pale catechu, contain slightly different chemicals, but they are used for the same purposes and at the same dose.
Catechu is used for diarrhea, swelling of the nose and throat, dysentery, swelling of the colon (colitis), bleeding, indigestion, osteoarthritis, and cancer.
People apply catechu directly to the skin for skin diseases, hemorrhoids, and traumatic injuries; to stop bleeding; and for dressing wounds.
Catechu is included in mouthwashes and gargles used for gum disease (gingivitis), pain and swelling inside the mouth (stomatitis), sore throat, and mouth ulcers.
In foods and beverages, catechu is used as a flavoring agent.

How does it work?

It is thought that catechu may contain chemicals that can decrease inflammation and kill bacteria.

Read more click –ACACIA  CATECHU Overview Information

Senegalia catechu - wikipedia

Emblica Officinalis

Indian gooseberry is a tree that grows in India and the Middle East. Indian gooseberry has been used in Ayurvedic medicine for thousands of years. Today people still use the fruit of the tree to make medicine.

Indian gooseberry is used for diabetes, high cholesterol, “hardening of the arteries” (atherosclerosis), pain and swelling of the pancreas (pancreatitis), cancer, upset stomach, eye problems, joint pain, diarrhea, dysentery, obesity, and “organ restoration.” It is also used to kill germs and reduce pain and swelling caused by the body’s reaction to injury or illness (inflammation).

How does it work?

Indian gooseberry seems to work by reducing total cholesterol levels, including the fatty acids called triglycerides, without affecting the “good cholesterol” called high-density lipoprotein (HDL).

Read more click - http://www.webmd.com/vitamins-supplements/ingredientmono-784-INDIAN%20GOOSEBERRY.aspx?activeIngredientId=784&activeIngredientName=INDIAN%20GOOSEBERRY

Emblica officinalis Gaertn. or Phyllanthus emblica Linn, commonly known as Indian gooseberry or amla, is arguably the most important medicinal plant in the Indian traditional system of medicine, the Ayurveda. Various parts of the plant are used to treat a range of diseases, but the most important is the fruit. The fruit is used either alone or in combination with other plants to treat many ailments such as common cold and fever; as a diuretic, laxative, liver tonic, refrigerant, stomachic, restorative, alterative, antipyretic, anti-inflammatory, hair tonic; to prevent peptic ulcer and dyspepsia, and as a digestive. Preclinical studies have shown that amla possesses antipyretic, analgesic, antitussive, antiatherogenic, adaptogenic, cardioprotective, gastroprotective, antianemia, antihypercholesterolemia, wound healing, antidiarrheal, antiatherosclerotic, hepatoprotective, nephroprotective, and neuroprotective properties. In addition, experimental studies have shown that amla and some of its phytochemicals such as gallic acid, ellagic acid, pyrogallol, some norsesquiterpenoids, corilagin, geraniin, elaeocarpusin, and prodelphinidins B1 and B2 also possess antineoplastic effects. Amla is also reported to possess radiomodulatory, chemomodulatory, chemopreventive effects, free radical scavenging, antioxidant, anti-inflammatory, antimutagenic and immunomodulatory activities, properties that are efficacious in the treatment and prevention of cancer. This review for the first time summarizes the results related to these properties and also emphasizes the aspects that warrant future research to establish its activity and utility as a cancer preventive and therapeutic drug in humans.

Read more click - http://www.ncbi.nlm.nih.gov/pubmed/21317655

Pterocarpus Marsupium

Common Name : Indian Kino, Gummy Kino, Marsupium

Chemical Constituents and Components : Main chemical components are liquiritigenin, isoliquiritigenin, pterosupin, epicatechin, pterostilbene, kinotannic acid, beta-eudesmol, marsupol, carpusin, marsupinol, kinoin and kino-red.

Action :
Pterostilbene:
1. It lowers the lipid and glucose level in body.
2. It shows significant reduction of glycosylated hemoglobin and an increase in total hemoglobin level.
3. It inhibits cell proliferation and induces apototic effect in tumor cell lines. 4. It shows moderate inhibition of cyclooxygenase (cox)-1 and weakly active against cox-2, thus shows potent antioxidant activity.
5. It inhibits electrolyte leakage caused by herbicide-induced oxidative damage.
Alkaloids:
1. It significantly lowers the high blood sugar level in body.
2. It raises the blood pressure and indirectly on sympathetic nerves. Tannins:
1. It shows scavenging activity against mitochondrial lipid peroxidation.
2. It causes significant decrease in cholesterol level.
3. It shows antimicrobial activity against bacteria and virus.

Curing Diseases :

1. It is useful in diabetes and heart problems.
2. It is helpful in controlling skin diseases.
3. It is also beneficial in the treatment of fractures, bruises, leprosy, leucoderma, constipation, depurative, rectalgia, ophthalmopathy, hemorrhages and rheumatoid arthritis.

Research Information : Pterocarpus marsupium shows strong antihyperlipdemic activity. It causes significant reduction of serum triglyceride, total cholesterol and LDL and VLDL cholesterol levels without any effect on the level of HDL-cholesterol. (Ref. Jahromi, M.A. and Ray, A.B., Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium, J Nat Prod. 1993 Jul; 56 (7): 989-994)

Possible Combinations : Pterocarpus marsupium + gymnema sylvestre + tinospora cordifolia (diabetes control)

Read more click - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991700/

Cinnamomum Tamala

Cinnamomum tamala, Indian bay leaf, also known as tejpat, Malabar leaf, Indian bark,  Indian cassia, or malabathrum is a tree within the Lauraceae family which is native to India, Nepal, Bhutan, and China. It can grow up to 20 m (66 ft) tall. It has aromatic leaves which are used for culinary and medicinal purposes. It is thought to have been one of the major sources of the medicinal plant leaves known in classic and medieval times as malabathrum (or malobathrum).

The bark is also sometimes used for cooking, although it is regarded as inferior to true cinnamon or cassia. In a recent study made by D.K.Sharma, C.Varshneya, P.Bharadwaj, and B.S.More of Department of Pharmacology and Toxicology COVAS,CSKHPKVV Palampur Himachal Pradesh India revealed that Methanolic Extract of C.tamala leaves @ 10mg/Kg to Alloxan induced diabetic rats for 15 days resulted in significant reduction in blood glucose level, blood glcosylated haemoglobin, LPO, serum AST, and ALT and significant increase in the antioxidant enzymes such as CAT, GSH, and SOD. However restoration of blood glucose and other parameters was much faster in Glibenclamide treated rats. Their studies indicated that C.tamala could be used as an adjunct therapy in Diabetes (Indian Vet. J. June 2012, 89(6): 72-74).

Source - http://en.wikipedia.org/wiki/Cinnamomum_tamala

Read more click - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195132/

Cyperus Rotundus

In light of the traditional claim of Cyperus rotundus in the treatment of diabetes, investigations were carried out to evaluate its effect on alloxan induced hyperglycemia in rats. Oral daily administration of 500 mg/kg of the extract (once a day for seven consecutive days) significantly lowered the blood glucose levels. This antihyperglycemic activity can be attributed to its antioxidant activity as it showed the strong DPPH radical scavenging action in vitro.

Read more click - http://www.ncbi.nlm.nih.gov/pubmed/17056202

Azadirachta Indica

Neem leaf is a traditional herb for treating diabetes and has been scientifically proven effective in treating and preventing diabetes. Oral doses of neem leaf extract significantly reduced insulin requirements for non-insulin dependent diabetes. Neem oil has also proven effective and has been able to inhibit increases in blood sugar levels by as much as 45% in test animals.

Neem leaf extract have been shown to reduce insulin requirements of diabetics without apparent effect on blood glucose levels. Different studies show insulin requirement reductions of between 20% and 50% for those who take five grams of dried neem leaf capsules. There are even anecdotal reports of diabetics chewing a single neem leaf daily that have been able to eliminate insulin injections completely.

Based on the many studies of neem's effects on insulin requirements, the Indian government has approved the sale by pharmaceutical companies of neem tablets for diabetics (Some of these preparations are really nothing more than powdered neem leaves).

Read more click –

Strengthening of antioxidant defense by Azadirachta indica in alloxan-diabetic rat tissues

CLICK - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487238/

CLICK - A study of hypoglycaemic effects of Azadirachta indica (Neem) in normaland alloxan diabetic rabbits.

Purified Asphaltum

ASPHALTUM (SHILAJIT) is also called DESTROYER OF DIABETES.

Asphaltum is particularly important in treating diabetes, where it has a good record of treatment of secondary diseases arising from diabetes, renal stones, bladder and urinary disorders, TB, leprosy, bronchitis, anemia and general debility.

Shilajit is very helpful in diabetes mellitus cases i.e. people with sugar problem. It helps in maintaining 

the normal sugar level in the body. Shilajit is considered as most supreme blood sugar modulator 

so as to control the sugar levels in the body.

Read more click - http://nowstopdiabetes.blogspot.in/p/shilajit-destroyer-of-diabetes.html

CLICK - http://www.blacklistedherb.com/article02.html

Trigonella Foenum – Graecum

Trigonella foenum-graecum (fenugreek) seeds have previously been shown to have hypoglycemic and hypocholesterolemic effects on type 1 and type 2 diabetes mellitus patients and experimental diabetic animals. The Trigonella foenum-graecum extract has now been investigated for its effects on general properties, blood glucose and blood lipid, and hemorheological parameters in experimental diabetic rats. Streptozotocin-induced diabetic rats were administrated by oral intragastric intubation separately with low dose (0.44 g/kg.d), middle dose (0.87 g/kg.d), high dose (1.74 g/kg.d) of Trigonella foenum-graecum extract, and Metformin HCl (0.175 g/kg.d) for 6 weeks. Compared with diabetic group, rats treated with Trigonella foenum-graecum extract had an increase in body weight and a decrease in kidney /body weight ratio (p<0.05). Compared with diabetic group, rats treated Trigonella foenum-graecum extract had lower blood glucose, glycated hemoglobin, triglycerides, total cholestrol and higher higher-density-lipoprotein-cholesterol in a dose-dependent manner (p<0.05). The plasma viscosity, whole blood viscosity of high shear rate (200 s-1) and low shear rate (40 s-1), erythrocyte sedimentation rate, whole blood reduction viscosity and platelet conglutination were significantly reduced in diabetic rats treated with high and middle doses of Trigonella foenum-graecum extract, but not in those treated with low dose of Trigonella foenum-graecum extract. It may be concluded that Trigonella foenum-graecum extract can lower kidney /body weight ratio, blood glucose, blood lipid levels and improve hemorheological properties in experimental diabetic rats following repeated treatment for 6 weeks.

Read more click

Effect of Trigonella foenum-graecum (fenugreek) extract on blood glucose, blood lipid and hemorheological properties in streptozotocin-induced diabetic rats.

Bhang Bhasm

Bang Bhasma is a powerful natural remedy used for the treatment of urinary disorders and general weakness. Bang bhasm is also found to be an effective natural product for genito-urinary disorders. It provides nourishment to the body cells and provides strength to the whole body for effective functioning. Bang bhasm is also an effective ayurvedic remedy for sexual disorders in men. Bang is a metal which is used in its pure form for the preparation of effective ayurvedic remedy for the treatment of various diseases.

Advantages

Bang bhasm is a natural product and does not produce any side effects even of taken regularly for a prolonged period of time. Bang bhasm is a natural metal which is used in non-toxic form for the preparation of this ayurvedic remedy. Bang bhasm is an effective ayurvedic product that helps in the treatment of genitor-urinary disorders and general weakness of the body.

Indications

Bang bhasm is indicated for normal functioning of different body systems such as genito-urinary system, general fatigue and sexual disorders. Bang bhasm is indicated for recurrent urinary infections, incontinence of urine, prostate hypertrophy in men, genital infections, etc. It is a very good product for increasing the body immunity against recurrent bacterial infections. It provides essential nutrients to body cells for increasing general body strength. Bang bhasm is also indicated for sexual disorders in men such as weak erections, premature ejaculation, night falls, weak tonicity of sexual organs, etc. It improves the health of sexual organs and increases sexual pleasure. Men suffering from sexual disorders may take this natural remedy for getting rid of sexual dysfunctions. Bang bhasm acts as a general tonic for whole body and improves overall functioning of all the organs of the body. It is also indicated for worm infections. Bang bhasm is a very good natural product indicated for mental fatigue. It provides nourishment to brain cells and helps to get normal sleep. Thus, bang bhasm is a natural and safe product which may be regularly taken for the improvement of body functions. Bang bhasm does not produce any side effects even if taken for a long time.

Yasad Bhasam                                      

Yashada bhasma (Calx of Yashada i.e. Zinc) which has its main indication in Prameha (Diabetes) and Netra vikaras (Eye disorders) was prepared according to the prescription in the Ayurvedic classics and subjected to various bhasma parikshas, including the Namburi Phased Spot Test (NPST), one of the qualitative tests described for various Ayurvedic preparations. NPST helps differentiate between, and thus identify, various bhasmas. It depends upon the pattern of the spot, which develops after a specific chemical reaction. Three market samples of Yashada bhasma, which were said to be Parada marita (incinerated using Mercury), were also subjected to the above tests and results compared. The various bhasmas exhibited marked differences in colour, and though NPST yielded desired results for all the samples, there were differences in their spot patterns and colour. The bhasma prepared in our department produced the most accurate results.

Yashada (Zinc) is one of the Puti Lohas (Metals with low melting points eg Lead, Tin etc.). Its bhasma (calx) has as its main indication, Prameha (Diabetes). In the 14^th century, Rasaka satva (the metallic extract of Zinc carbonate/Zinc oxide) was also independently known by the name "Yashada". Since then, its bhasma has been in therapeutic use for various disorders including Prameha (Diabetes), Pandu (Anemia), Vatavyadhis (Neuro-muscular diseases), and Netra vikaras (Eye diseases). Yashada bhasma prepared using Parada (Mercury) is considered the best in Rasashastra[1] branch of Ayurveda. However, in this competitive, commercialized world, the quality of a bhasma is always open to question. For bhasma quality assessment, various bhasma parikshas (tests) have been described in the classics.

Click to read more - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131774/

Guar Gum    

Guar gum is a fiber from the seed of the guar plant.

Guar gum is used as a laxative. It is also used for treating diarrhea, irritable bowel syndrome (IBS), obesity, and diabetes; for reducing cholesterol; and for preventing “hardening of the arteries” (atherosclerosis).

In foods and beverages, guar gum is used as a thickening, stabilizing, suspending, and binding agent.

In manufacturing, guar gum is used as a binding agent in tablets, and as a thickening agent in lotions and creams.

How does it work?

Guar gum is a fiber that normalizes the moisture content of the stool, absorbing excess liquid in diarrhea, and softening the stool in constipation. It also might help decrease the amount of cholesterol and glucose that is absorbed in the stomach and intestines.

There is some interest in using guar gum for weight loss because it expands in the intestine, causing a sense of fullness. This may decrease appetite.

Click to read more - http://www.webmd.com/vitamins-supplements/ingredientmono-919-GUAR%20GUM.aspx?activeIngredientId=919&activeIngredientName=GUAR%20GUM

Gum Acacia    

Acacia is the gum that is exuded from the acacia tree. It’s a dietary fiber that can dissolve in water.

As a medicine, acacia is taken by mouth to reduce cholesterol levels and to help increase weight loss.

In manufacturing, acacia is used as a pharmaceutical ingredient in medications for throat or stomach inflammation and as a film-forming agent in peel-off skin masks.

Don’t confuse acacia with sweet acacia (Acacia farnesiana).

How does it work?

Acacia is a source of dietary fiber. It tends to make people feel full, so they might stop eating earlier than they otherwise would. This might lead to weight loss and reduced cholesterol levels.

Read more click - ACACIA Overview InformationPharmacognosy of Acacia - Wikipedia

Sodium Benzoate
Sodium benzoate has the chemical formula NaC₇H₅O₂; it is a widely used food preservative, with E number E211. It is the sodium salt of benzoic acid and exists in this form when dissolved in water. It can be produced by reacting sodium hydroxide with benzoic acid. Benzoic acid occurs naturally at low levels in cranberries, prunes, greengage plums, cinnamon, ripe cloves, and apples.

Read more click - http://en.wikipedia.org/wiki/Sodium_benzoate